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✅ Description:
Mitaprex 30 contains Mirtazapine which belongs to the group of medicines called Antidepressants. It is used in adults to manage depression. Depression is a mood disorder characterized by persistent feelings of sadness, loss of interest, feeling guilty or worthless, attention impairment, lack of energy, suicidal thoughts, and slow or abnormal physical movements.
Mitaprex 30 can be taken with or without meals. It may take around 1-2 weeks for Mitaprex 30 to start working and you may notice improvement in your condition only after 2-4 weeks of therapy. Therefore, take Mitaprex 30 for the duration recommended by your doctor to achieve better results.
Before taking Mitaprex 30 inform your doctor if you have any liver, kidney, or heart problems. You must also inform your doctor if you have jaundice, diabetes, glaucoma, low blood pressure, previous history of fits, suicidal thoughts, or other mental illnesses (such as manic depression or schizophrenia) as a precaution.
Safety Advices
Alcohol
UNSAFE
Avoid consumption of alcohol while taking Mitaprex 30 as it may make you feel dizzier.
Pregnancy
CONSULT YOUR DOCTOR
Mitaprex 30 should be used with caution in pregnant women and in women who think that they might be pregnant or planning to have a baby. Therefore, consult your doctor before taking it.
Breastfeeding
CONSULT YOUR DOCTOR
Mitaprex 30 should be used with caution in breastfeeding women. Therefore, consult your doctor before taking it.
Driving
UNSAFE
Do not drive or operate any heavy tools or machines if you experience dizziness or tiredness after taking Mitaprex 30.
Kidney
CONSULT YOUR DOCTOR
Mitaprex 30 should be used with caution in patients with kidney problems. Therefore, consult your doctor before taking it.
Liver
CONSULT YOUR DOCTOR
Mitaprex 30 should be used with caution in patients with liver problems (such as jaundice). Therefore, consult your doctor before taking it.
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✔️ Uses of Mitaprex 30
✔️ How does Mitaprex 30 work?
Mitaprex works by increasing the levels of chemical messengers (serotonin and noradrenaline), natural substances in the brain that help maintain mental balance.
✔️ Side Effects of Mitaprex 30
Common side effects include:
- Dizziness
- Drowsiness
- Dry mouth
- Increased appetite
- Weight gain
✔️ Quick Suggestions:
- Mitaprex 30 starts to work more quickly than other antidepressants.
- Avoid driving or operating dangerous machinery as it may decrease alertness.
- Avoid consuming alcohol when taking the Mirtazapine, as it may cause excessive drowsiness and calmness.
- If your doctor asks you to stop Mirtazapine, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly.
- Notify your doctor immediately if you develop a sore throat fever or stomatitis during treatment with Mirtazapine.
✔️ Indications
Mitaprex Tablets contain Mirtazapine, which is indicated for the treatment of Major Depressive Disorder (MDD).
✔️ Pharmacology
- Pharmacodynamics: The precise mechanism is unknown, but it is believed that Mirtazapine increases central noradrenergic and serotonergic activity by antagonizing α2-adrenergic receptors, which results in enhanced neurotransmitter release. It also acts as an antagonist on 5-HT2 and 5-HT3 receptors, leading to reduced serotonergic side effects like nausea. Additionally, Mirtazapine’s antagonism at H1 receptors accounts for its sedative effects.
- Pharmacokinetics: After oral intake, Mirtazapine is quickly absorbed and reaches peak plasma levels in about 2 hours. Its half-life is 20-40 hours, which allows for once-daily dosing. Mirtazapine is metabolized primarily by demethylation and oxidation and excreted through urine and feces.
✔️ Dosage & Administration of Mitaprex 30
- Adult Dose: The starting dose is 15 mg/day, typically in the evening before sleep. If needed, the dose can be increased up to 30-45 mg/day. Dose adjustments should occur no sooner than every 1-2 weeks to monitor therapeutic response.
- Pediatric Use: Not recommended for children.
- Missed Dose: Take as soon as remembered unless it is close to the next dose; do not double the dose.
✔️ Interaction
- Monoamine Oxidase Inhibitors (MAOIs): Avoid combining with MAOIs and other serotonergic drugs like tryptophan, SSRIs, venlafaxine, and tramadol due to the risk of serotonin syndrome.
- Other Interactions: Caution with Carbamazepine, Phenytoin, Cimetidine, and avoid alcohol and diazepam due to increased sedative effects.
✔️ Contraindications
- Hypersensitivity: Contraindicated in patients with known hypersensitivity to Mirtazapine.
- MAOIs: Do not use with MAOIs or within 14 days of discontinuing an MAOI.
✔️ Pregnancy & Lactation
Pregnancy Category C: Use only if the potential benefits justify the risk. Patients should notify their physician if pregnant or breastfeeding.
✔️ Precautions & Warnings
- Suicidal Thoughts: Monitor for anxiety, panic attacks, insomnia, irritability, agitation, and suicidal thoughts, especially during the early stages of treatment.
- Agranulocytosis Risk: Warn patients about the potential for agranulocytosis.
- Sedation: May impair motor skills and judgment due to sedative effects.
- Liver Function: Elevations in ALT (SGPT) levels may occur.
✔️ Storage:
Store below 30ºC, away from light and moisture, and keep out of reach of children.
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